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| 产品编号 | KMH427 |
|---|---|
| 产品名称 | Recombinant Human CD278/ICOS Protein, Fc Tag |
| 产品描述 | Recombinant Human CD278/ICOS Protein, Fc Tag (KMH427) contains the human ICOS(Met1-Lys140) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
| 分子名称 | ICOS |
| 产品别称 | AILIM, CD278, CVID1, inducible T cell costimulator |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | Q9Y6W8 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS, pH7.5 |
| 分子量 | 39.99 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
