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产品编号 | KMP2352 |
---|---|
产品名称 | Marmoset HAVCR2 Protein, His Tag |
产品描述 | The Marmoset HAVCR2 Protein(KMP2352) is produced in HEK293 Cells and the target gene encoding Glu21-Ile190 is expressed with a 6His tag at the C-terminus. |
物种 | Marmoset |
宿主 | HEK293 Cells |
规格 | 50ug, 100ug, 200ug |
纯化方式 | Affinity purification |
内毒素水平 | <1.0 EU/ug determined by the LAL method |
缓冲体系 | PBS, pH7.4 |
SDS-PAGE | ![]() |
产品背景 | T cell immunoglobulin and mucin domain-3(TIM3), also called hepatitis A virus cellular receptor 2(HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1(PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC. |
保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
说明 | This product is for research use only. |
编号 | 产品名称 | 物种 | 宿主 | 应用 | 规格 | 询价 |
---|---|---|---|---|---|---|
KMPH1552 | Human HAVCR2/TIM3 Protein, Fc & His Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH1553 | Human HAVCR2/TIM3 Protein, His Tag | Human | HEK293 Cells | 50ug, 100ug | ||
MOP1874 | Mouse HAVCR2/TIM3 Protein, Fc Tag | Mouse | HEK293 Cells | 50ug, 100ug | ||
MOP1875 | Mouse HAVCR2/TIM3 Protein, His Tag | Mouse | HEK293 Cells | 50ug, 100ug | ||
KMPH5907 | Human HAVCR2/TIM3 Protein, Fc Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH5908 | Human HAVCR2/TIM3 Protein, Fc & His Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH5909 | Human HAVCR2/TIM3 Protein, Fc Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH5910 | Human HAVCR2/TIM3 Protein, Strep Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH5911 | Human HAVCR2/TIM3 Protein, Fc & His Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH5912 | Human HAVCR2/TIM3 Protein, Fc Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMPH6035 | Human HAVCR2/TIM3 Protein, Fc Tag | Human | HEK293 Cells | 50ug, 100ug | ||
KMH513 | Recombinant Human HAVCR2 Protein, His Tag | Human | Mammalian cells | 50ug, 100ug | ||
MOP2174 | Recombinant Mouse Havcr2/Tim-3 Protein, His Tag | Mouse | Mammalian cells | 50ug, 100ug | ||
MOP2294 | Recombinant Mouse TIM-3/Havcr2 Protein, His Tag | Mouse | Mammalian cells | 50ug, 100ug | ||
KMH1807 | Recombinant Human TIM-3/HAVCR2 C-fc Protein, Fc & His Tag | Human | Mammalian cells | 50ug, 100ug | ||
MOP2295 | Recombinant Mouse TIM-3/Havcr2 C-fc Protein, Fc Tag | Mouse | Mammalian cells | 50ug, 100ug | ||
KMH1808 | Recombinant Human TIM-3/HAVCR2 Protein, His Tag | Human | Mammalian cells | 50ug, 100ug | ||
MOP2296 | Recombinant Mouse TIM-3/Havcr2 Protein, His Tag | Mouse | Mammalian cells | 50ug, 100ug | ||
PA7062 | Rabbit Anti-Human HAVCR2 pAb | Human | Rabbit | WB, IF | 50ul, 100ul | |
PA7063 | Rabbit Anti-Human HAVCR2 pAb | Human | Rabbit | IHC, IF | 50ul, 100ul | |
PA7064 | Rabbit Anti-Human HAVCR2 pAb | Human | Rabbit | WB, IHC | 50ul, 100ul | |
PA10794 | Rabbit Anti-Human HAVCR2 pAb | Human | Rabbit | WB | 50ul, 100ul | |
PA12960 | Rabbit Anti-Human HAVCR2 pAb | Human | Rabbit | WB, IHC | 50ul, 100ul | |
KMP1834 | Recombinant Human HAVCR2 Protein | Human | HEK293 cells | 50ug, 100ug | ||
KMP2288 | Human HAVCR2 Protein, mFc Tag | Human | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2301 | Human HAVCR2 Protein, Fc Tag, Avi Tag | Human | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2310 | Cynomolgus HAVCR2 Protein, Fc Tag | Cynomolgus | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2336 | Mouse HAVCR2 Protein, Fc Tag | Mouse | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2340 | Mouse HAVCR2 Protein, His Tag | Mouse | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2354 | Mouse HAVCR2 Protein, His Tag | Mouse | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2382 | Human HAVCR2 Protein, Fc Tag, His Tag | Human | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2399 | Cynomolgus HAVCR2 Protein, His Tag | Cynomolgus | HEK293 Cells | 50ug, 100ug, 200ug | ||
KMP2404 | Human HAVCR2 Protein, His Tag | Human | HEK293 Cells | 50ug, 100ug, 200ug |