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| 产品编号 | KMH152 |
|---|---|
| 产品名称 | Recombinant Human CD3E Protein, His Tag |
| 产品描述 | Recombinant Human CD3E Protein, His Tag (KMH152) contains the human CD3E(Met1-Asp126) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | CD3E |
| 产品别称 | T3E, TCRE, IMD18, CD3e molecule |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P07766 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS, pH7.5 |
| 分子量 | 12.69 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
