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| 产品编号 | KMH185 |
|---|---|
| 产品名称 | Recombinant Human CD30 Protein, His Tag |
| 产品描述 | Recombinant Human CD30 Protein, His Tag (KMH185) contains the human TNFRSF8(Met1-Lys379) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | TNFRSF8 |
| 产品别称 | CD30, Ki 1, D1S166E, TNFRSF8, TNF receptor superfamily member 8 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P28908 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 41.8 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | CD3/TNFRSF8, a type I transmembrane glycoprotein belonging to the TNF receptor superfamily and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. CD3 is associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus is a useful marker in distinguishing between these germ cell tumors. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
