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Recombinant Human CD40 Protein, His Tag产品信息
产品编号 KMH195
产品名称 Recombinant Human CD40 Protein, His Tag
产品描述 Recombinant Human CD40 Protein, His Tag (KMH195) contains the human CD40(Met1-Arg193) was fused with the C-terminal His Tag and expressed in Mammalian cells.
分子名称 CD40
产品别称 p50, Bp50, CDW40, TNFRSF5, CD40 molecule
规格 50ug, 100ug
物种 Human
宿主 Mammalian cells
蛋白家族 CD molecule
编录号 P25942
纯度 ≥90% as determined by SDS-PAGE
内毒素水平 < 1.0 EU per ug of the protein as determined by the LAL method.
缓冲体系 PBS, pH7.5
分子量 22.32 kDa
纯化方式 Affinity Purification
产品背景 CD4 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD4L) on TH cells to CD4 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions.
保存条件 Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
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