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| 产品编号 | KMH328 |
|---|---|
| 产品名称 | Recombinant Human CD155/PVR Protein, His Tag |
| 产品描述 | Recombinant Human CD155/PVR Protein, His Tag (KMH328) contains the human PVR(Met1-Asn343) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | PVR |
| 产品别称 | PVS, HVED, CD155, NECL5, TAGE4, Necl 5, PVR cell adhesion molecule |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P15151 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 37.73 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
