周一至周六
8:00-18:00
服务电话:400-621-6806
地址:天津市武清区国际企业社区A5号楼四层,301700
邮箱:
产品编号 | KMH409 |
---|---|
产品名称 | Recombinant Human CD258/TNFSF14 Protein, His Tag |
产品描述 | Recombinant Human CD258/TNFSF14 Protein, His Tag (KMH409) contains the human TNFSF14(Leu59- Val240) was fused with the N-terminal His Tag and expressed in Mammalian cells. |
分子名称 | TNFSF14 |
产品别称 | LTg, CD258, HVEML, LIGHT, TNF superfamily member 14 |
规格 | 50ug, 100ug |
物种 | Human |
宿主 | Mammalian cells |
蛋白家族 | CD molecule |
编录号 | O43557 |
纯度 | ≥90% as determined by SDS-PAGE |
内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
缓冲体系 | PBS |
分子量 | 20.02 kDa |
纯化方式 | Affinity Purification |
产品背景 | LIGHT is a type II transmemebrane protein and a member of the TNF cytokine family also referred to as TNFSF14 and it is identical with HVEM ligand. LIGHT is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3). |
保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |