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| 产品编号 | KMH614 |
|---|---|
| 产品名称 | Recombinant Human 4-1BB/TNFRSF9/CD137 Protein, His Tag |
| 产品描述 | Recombinant Human 4-1BB/TNFRSF9/CD137 Protein, His Tag (KMH614) contains the human TNFRSF9(Leu24-Gln186) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | TNFRSF9 |
| 产品别称 | ILA, 4 1BB, CD137, CDw137, TNF receptor superfamily member 9 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | Other protein |
| 编录号 | Q07011 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 18.04 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | 4-1BB is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is alternatively known as TNFRSF9, CD137, and ILA. The 255 amino acid human 4-1BB is a type I transmembrane protein having in its extracellular domain four of the cysteine-rich motifs that are characteristic of the TNF receptor superfamily. The 3 KD glycoprotein exists both as a monomer and as a dimer on T cells. The human and mouse proteins share 6% amino acid identity.A DNA sequence encoding the N-terminal fragment (Met 1– Gln 186) of the extracellular domain of human 4-1BB (NP_1552.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
