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产品编号 | KMP2311 |
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产品名称 | Mouse CD48 Protein, His Tag |
产品描述 | The Mouse CD48 Protein(KMP2311) is produced in HEK293 Cells and the target gene encoding Phe23-Arg216 is expressed with a 6His tag at the C-terminus. |
物种 | Mouse |
宿主 | HEK293 Cells |
规格 | 50ug, 100ug, 200ug |
纯化方式 | Affinity purification |
内毒素水平 | <1.0 EU/ug determined by the LAL method |
缓冲体系 | PBS, pH7.4 |
SDS-PAGE | |
产品背景 | CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. Among dendritic cells(DC), CD48 is selectively expressed on circulating myeloid DC and resident bone marrow and thymus DC. CD2, 2B4, and heparan sulfate function as CD48 ligands. CD48 is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48 expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation. |
保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
说明 | This product is for research use only. |