w66最给力的老牌生物科技（天津）有限公司
400-621-6806
周一至周六
8:00-18:00
服务电话：400-621-6806
地址：天津市武清区国际企业社区A5号楼四层，301700
邮箱：
| 产品编号 | KMP2531 |
|---|---|
| 产品名称 | Human CD40L Protein, His Tag |
| 产品描述 | The Human CD40L Protein(KMP2531) is produced in E. coli. The target gene encoding the soluble form of human CD40L (NP_000065.1) (Glu 108-Leu 261) is expressed with an initial Met at the N-terminus and a polyHistide tag at the C-terminus. |
| 分子名称 | CD40L |
| 产品别称 | 肿瘤坏死因子相关激活蛋白, Human CD40L Protein, His Tag, CD40L |
| 物种 | Human |
| 宿主 | E. coli |
| 规格 | 50ug, 100ug, 200ug |
| 纯度 | >95% as determined by SDS-PAGE |
| 纯化方式 | Affinity purification |
| 内毒素水平 | <1.0 EU/ug determined by the LAL method |
| 缓冲体系 | PBS, 10% Glycerol, pH7.4 |
| 产品背景 | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation. |
| 保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| 说明 | This product is for research use only. |
