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产品编号 | KMH1238 |
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产品名称 | Recombinant Human ICOS Protein, Fc Tag |
产品描述 | Recombinant Human ICOS Protein, Fc Tag (KMH1238) contains the human ICOS(Glu21-Phe141) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
分子名称 | ICOS |
产品别称 | AILIM, CD278, CVID1, inducible T cell costimulator |
规格 | 50ug, 100ug |
物种 | Human |
宿主 | Mammalian cells |
蛋白家族 | Other protein |
编录号 | Q9Y6W8 |
纯度 | ≥90% as determined by SDS-PAGE |
内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
缓冲体系 | PBS |
分子量 | 38.31 kDa |
纯化方式 | Affinity Purification |
产品背景 | Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases. |
保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |