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| 产品编号 | KMH385 |
|---|---|
| 产品名称 | Recombinant Human CD223/LAG3 Protein, His Tag |
| 产品描述 | Recombinant Human CD223/LAG3 Protein, His Tag (KMH385) contains the human LAG3(Met1-Leu450) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | LAG3 |
| 产品别称 | CD223, lymphocyte activating 3 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P18627 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | Supplied as solution form in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 7.5, 150 mM NaCl. |
| 分子量 | 49.61 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
