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| 产品编号 | KMH518 |
|---|---|
| 产品名称 | Recombinant Human 4-1BBL/TNFSF9 Protein, His Tag |
| 产品描述 | Recombinant Human 4-1BBL/TNFSF9 Protein, His Tag (KMH518) contains the human TNFSF9(Ala50-Glu254) was fused with the N-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | TNFSF9 |
| 产品别称 | CD137L, TNLG5A, 4 1BB L, TNF superfamily member 9 |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | Immune checkpoint |
| 编录号 | P41273 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS, pH7.5 |
| 分子量 | 22.64 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | CD137 is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), 4-1BB and induced by lymphocyte activation (ILA). The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
