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| 产品编号 | KMP3697 |
|---|---|
| 产品名称 | Cynomolgus TNFSF9 Protein, hFc Tag |
| 产品描述 | The Cynomolgus TNFSF9 Protein(KMP3697) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus TNFSF9 (XP_015296398.1) (Arg68-Glu251) is expressed with the Fc region of human IgG1 at the N-terminus. The purified protein is biotinylated in vitro. |
| 分子名称 | TNFSF9 |
| 物种 | Cynomolgus |
| 宿主 | HEK293 Cells |
| 规格 | 50ug, 100ug, 200ug |
| 纯度 | >95% as determined by SDS-PAGE |
| 纯化方式 | Affinity purification |
| 内毒素水平 | <1.0 EU/ug determined by the LAL method |
| 缓冲体系 | PBS, pH7.4 |
| 产品背景 | 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases. |
| 保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| 说明 | This product is for research use only. |
