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| 产品编号 | KMH183 |
|---|---|
| 产品名称 | Recombinant Human CD28 Protein, Fc Tag |
| 产品描述 | Recombinant Human CD28 Protein, Fc Tag (KMH183) contains the human CD28(Met1-Pro152) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
| 分子名称 | CD28 |
| 产品别称 | Tp44, CD28 molecule |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | P10747 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS, pH7.5 |
| 分子量 | 42.63 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | CD28 (Cluster of Differentiation 28) is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. It is expressed on the cell surface as disulfide-linked homodimer or as monomer. CD28 is the receptor for B7.1 (CD8) and B7.2 (CD86). When activated by Toll-like receptor ligands, the B7.1 expression is upregulated in antigen presenting cells (APCs). The B7.2 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
