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| 产品编号 | KMP2892 |
|---|---|
| 产品名称 | Human CD28 Protein, mFc Tag |
| 产品描述 | The Human CD28 Protein(KMP2892) is produced in HEK293 Cells. The target gene encoding the Human / Cynomolgus / Rhesus CD28 (P10747-1) (Met1-Pro152) is expressed with the Fc region of mouse IgG2a at the C-terminus. |
| 分子名称 | CD28 |
| 产品别称 | T细胞特异性表面糖蛋白CD28, Human CD28 Protein, mFc Tag, CD28 |
| 物种 | Human |
| 宿主 | HEK293 Cells |
| 规格 | 50ug, 100ug, 200ug |
| 纯度 | >95% as determined by SDS-PAGE |
| 纯化方式 | Affinity purification |
| 内毒素水平 | <1.0 EU/ug determined by the LAL method |
| 缓冲体系 | PBS, pH7.4 |
| 产品背景 | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. |
| 保存条件 | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| 说明 | This product is for research use only. |
