w66最给力的老牌生物科技（天津）有限公司
400-621-6806
周一至周六
8:00-18:00
服务电话：400-621-6806
地址：天津市武清区国际企业社区A5号楼五层，301700
邮箱：
| 产品编号 | KMH421 |
|---|---|
| 产品名称 | Recombinant Human CD272/BTLA Protein, His Tag |
| 产品描述 | Recombinant Human CD272/BTLA Protein, His Tag (KMH421) contains the human BTLA(Met1-Ser150) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | BTLA |
| 产品别称 | BTLA1, CD272, B and T lymphocyte associated |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | CD molecule |
| 编录号 | Q7Z6A9 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | Supplied as solution form in 50 mM Tris-HCl, pH 8.0, 150 mM NaCl./Lyophilized from 50 mM Tris-HCl, pH 8.0, 150 mM NaCl. |
| 分子量 | 14.68 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
