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| 产品编号 | KMH761 |
|---|---|
| 产品名称 | Recombinant Human BTLA Protein, His Tag |
| 产品描述 | Recombinant Human BTLA Protein, His Tag (KMH761) contains the human BTLA(Lys31-Leu150) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | BTLA |
| 产品别称 | BTLA1, CD272, B and T lymphocyte associated |
| 规格 | 50ug, 100ug |
| 物种 | Human |
| 宿主 | Mammalian cells |
| 蛋白家族 | Other protein |
| 编录号 | Q7Z6A9-2 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 13.2 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
