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Rat CD86 Protein, His Tag产品信息
产品编号 KMP2296
产品名称 Rat CD86 Protein, His Tag
产品描述 The Rat CD86 Protein(KMP2296) is produced in HEK293 Cells and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus.
物种 Rat
宿主 HEK293 Cells
规格 50ug, 100ug, 200ug
纯化方式 Affinity purification
内毒素水平 <1.0 EU/ug determined by the LAL method
缓冲体系 PBS, pH7.4
SDS-PAGE
产品背景 T-lymphocyte activation antigen CD86(B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
保存条件 Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
说明 This product is for research use only.
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