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| 产品编号 | MOP2074 |
|---|---|
| 产品名称 | Recombinant Mouse B7-2/Cd86 Protein, His Tag |
| 产品描述 | Recombinant Mouse B7-2/Cd86 Protein, His Tag (MOP2074) contains the mouse Cd86(Val24-Lys244) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| 分子名称 | Cd86 |
| 产品别称 | B7, B70, MB7, B7 2, B7.2, CLS1, Ly58, ETC 1, Ly 58, MB7 2, Cd28l2, TS/A 2, CD86 antigen |
| 规格 | 50ug, 100ug |
| 物种 | Mouse |
| 宿主 | Mammalian cells |
| 蛋白家族 | Other protein |
| 编录号 | P42082 |
| 纯度 | ≥90% as determined by SDS-PAGE |
| 内毒素水平 | < 1.0 EU per ug of the protein as determined by the LAL method. |
| 缓冲体系 | PBS |
| 分子量 | 24.31 kDa |
| 纯化方式 | Affinity Purification |
| 产品背景 | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 2 - 1 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. |
| 保存条件 | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
