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Human HAVCR2 Protein, His Tag产品信息
产品编号 KMP2404
产品名称 Human HAVCR2 Protein, His Tag
产品描述 The Human HAVCR2 Protein(KMP2404) is produced in HEK293 Cells and the target gene encoding Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
物种 Human
宿主 HEK293 Cells
规格 50ug, 100ug, 200ug
纯化方式 Affinity purification
内毒素水平 <1.0 EU/ug determined by the LAL method
缓冲体系 20mM PB, 150mM NaCl, pH7.4
SDS-PAGE
产品背景 T-Cell Membrane Protein 3(TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence(aa 1-21), an extracellular region(aa 22-202) with one Ig-like V-type domain, a transmembrane segment(aa 203-223), and a cytoplasmic domain(aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte(Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
保存条件 Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
说明 This product is for research use only.
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